| 1. | Effects of gstt on early atherosclerotic lesion of aortic intima in rabbits
蒺藜总皂苷对家兔主动脉内膜粥样硬化病变的影响 |
| 2. | Patterns of shear stress may contribute to the focal distribution atherosclerotic lesions
研究发现，血液流动力的形式与动脉粥样硬化的发生发展有密切的关系。 |
| 3. | The lipid and calcium content in serum , and the aortic wall , the hemorrheologicvariation and the aortic atherosclerotic lesion were investigated in rabbits fed with cholesterol and diltiazem
译：给家兔喂饲胆固醇和硫氮艹卓酮，观察其血清和主动脉壁脂质及钙的含量，血流动力学变化和主动脉壁粥样硬化病变的程度 |
| 4. | Here we show that 27 - hydroxycholesterol ( 27hc ) , an abundant cholesterol metabolite that is elevated with hypercholesterolemia and found in atherosclerotic lesions , is a competitive antagonist of estrogen receptor action in the vasculature
在此我们发现27 -羟基胆甾醇( 27hc )是一种含量丰富的胆固醇代谢产物，它的过量引起高胆固醇血症并存于粥样硬化病变中，在血管中是雌激素受体竞争性拮抗剂。 |
| 5. | Atherosclerotic lesions long have been known to occur near vascular branching points . study have identified in these predisposed areas , hemodynamic shear stress , the frictional force acting on the endothulial cell surface as a result of blood flow , is weaker than in protected regions
从对动脉粥样硬化的临床及病理研究中，我们已确定动脉粥样硬化好发于血管的分支及弯曲处，该处血流方式不同于血管的其他部位。 |
| 6. | Deficiency of apoe may promote to produce and develop atherosclerotic lessions . the apoe gene - targeted mice will result in marked regression of both early and advanced atherosclerotic lesions by injected apoe recombinant protein , or by transfected adviral vector with apoe cdna to express human apoe transgene in liver , or by transplantation of bone marrow with normal rat apoe gene . this demonstrates that apoe gene and its expressing product can inhibit progression of atherogenesis . apoe3 has a more effective prevention from as than apoe2 and apoe4
Apoe的缺失可促进动脉粥样硬化的发生发展，给apoe基因敲除鼠反复注射apoe重组蛋白、在肝组织中用腺病毒载体表达apoe蛋白、移植带有正常apoe基因的小鼠骨髓，都能使apoe基因敲除鼠的动脉粥样硬化得到回复，表明apoe基因及其表达产物对动脉粥样硬化的发生具有抑制作用， apoe _ 3对动脉硬化的阻抑作用要比apoe _ 2和apoe _ 4都明显。 |
